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How to Build an AI Life Science Platform like Causaly?

How to Build an AI Life Science Platform like Causaly?

AI is reshaping life sciences by doing more than speeding up data analysis; it’s changing the way discoveries happen. Platforms like Causaly are moving past the limitations of correlation-based research and instead revealing the causes behind biological events. This shift allows scientists to pinpoint why certain drugs work, identify biomarkers with real clinical relevance, and map the underlying mechanisms of diseases. 

For pharmaceutical and biotech teams, that means fewer blind spots, faster iteration, and a higher chance of breakthrough results. It’s not just about efficiency, it’s about making the leap from “what’s happening” to “why it’s happening,” and that’s where the next generation of treatments will be born.

With the growing need for smarter research tools, we’ve helped organizations build AI-powered life science platforms that enable better decision-making through causal data analysis. These systems combine machine learning and AI to detect patterns that can predict disease outcomes, optimize clinical trials, and speed up the identification of effective drugs. With IdeaUsher’s extensive expertise in integrating advanced AI capabilities, we can help you develop a platform that enhances your research accuracy, speed, and scalability. Through this blog, we’re excited to share our insights and guide you in building a powerful, AI-driven platform that drives your success.

Key Market Takeaways for AI Life Science Platforms

According to PrecedenceResearch, the AI-driven life sciences market is growing rapidly, with projections showing it will expand from USD 2.22 billion in 2024 to USD 6.28 billion by 2034. This growth is largely fueled by AI’s ability to streamline processes in drug discovery, diagnostics, and personalized medicine, making it easier to analyze complex biological data more efficiently.

Key Market Takeaways for AI Life Science Platforms

Source: PrecedenceResearch

AI platforms are becoming invaluable tools for researchers and companies. Innovators like Verge Genomics, Tempus, and AI Superior are using AI to drive faster drug development, improve diagnostic accuracy, and enhance clinical research. These tools are allowing life science professionals to make better decisions, quicker and with more precision.

Partnerships are also helping to push the field forward. Collaborations between companies like PathAI and Discovery Life Sciences, along with IQVIA and NVIDIA, are accelerating the adoption of AI solutions in healthcare. These alliances are key to improving research workflows and advancing patient care by integrating AI into everyday practices.

What Is an AI Life Science Platform?

An AI life science platform is a specialized digital environment that uses artificial intelligence and machine learning to make sense of massive, complex biomedical datasets. These systems help researchers, biotech companies, and healthcare organizations uncover patterns, generate hypotheses, and make faster, evidence-based decisions in areas like drug discovery, clinical research, and precision medicine.

Rather than replacing scientists, these platforms act as powerful analytical partners, sifting through information that would take humans months or years to process. They often combine:

  • Natural Language Processing (NLP) to read and interpret scientific text.
  • Knowledge graphs to map relationships between genes, diseases, drugs, and outcomes.
  • Predictive models to forecast how interventions might work.
  • Generative models to propose new molecules or research directions.

What Can They Do?

  • Mine the literature – Pull relevant findings from millions of papers and patents in seconds.
  • Support drug discovery – Predict drug–target interactions and possible repurposing opportunities.
  • Refine clinical trials – Identify the best patient cohorts, trial sites, and potential risks.
  • Spot biomarkers – Detect genetic or molecular signatures linked to diseases.

The result: faster insights, lower R&D costs, and fewer dead ends in the research process.


Types of AI Life Science Platforms

TypeDescriptionExampleExample Use
Literature Mining PlatformsUse NLP to extract facts and links from scientific text.Causaly – Maps cause-and-effect from literature.Researcher finds all evidence linking a gene to a cancer type.
Clinical Trial Analytics ToolsUse AI to improve trial design and recruitment.Saama AI Clinical Trial Analytics – Predicts trial risks.Pharma picks sites with best patient availability and retention.
Drug–Target Prediction EnginesPredict drug–target interactions and repurposing options.BenevolentAI – Finds new uses for existing drugs.Biotech repurposes an approved drug for a rare disorder.
Multi-Omics Data Analysis PlatformsIntegrate multi-omics data to reveal disease mechanisms.DNAnexus – Analyzes large-scale genomic datasets.Hospital matches cancer patients with targeted therapies.

How Does the Causaly Platform Work?

Causaly is designed to help scientists go beyond keyword searches and uncover real cause-and-effect relationships hidden in biomedical literature. Its core technology focuses on understanding how biological mechanisms work, not just whether terms appear together.

1. From Correlation to Causation

Most search tools surface papers where two terms co-occur. Causaly is different — it’s trained to recognize when the literature shows a genuine causal link.

It uses:

  • Advanced natural language processing to detect cause-and-effect phrases like “inhibits,” “induces,” or “results in.”
  • Semantic models that separate loose associations from true mechanistic evidence.
  • Biomedical context filters to ignore statistically weak or irrelevant findings.

Example: A conventional search might show that “coffee” and “liver cancer” appear in the same paper. Causaly can determine whether the study actually finds that coffee consumption reduces liver cancer risk.


2. A Precision-Built Biomedical Knowledge Graph

At the heart of Causaly is a constantly updated biomedical database. It maps over 500 million carefully curated links between drugs, diseases, genes, and biomarkers, all pulled from more than 30 million papers and clinical trials. For key findings, experts verify the data by hand, and each link gets a confidence score so you know exactly how strong the evidence is.


3. Generative AI with Verified Sources

Causaly’s assistant doesn’t just give you an answer, it shows you exactly where it came from. Every response is pulled from its knowledge graph using a RAG model, complete with a confidence score and the reasoning behind it. That way, even for regulatory work, you’ve got a clear paper trail you can trust.


4. Secure Data Integration

Causaly lets you merge public research with your own data without sacrificing security. You can build private knowledge graphs from internal documents, connect lab systems or EHRs, and control who sees what with role-based access. Even sensitive details stay protected through differential privacy safeguards.


5. Automated Hypothesis Generation

Causaly can uncover links you might never think to check, using graph neural networks to spot hidden pathways and multi-step reasoning to connect the dots. It scores each finding to highlight promising drug repurposing ideas and lets you explore them through interactive visual maps. That’s how a heart drug might suddenly look like a candidate for a brain disorder.


Why Companies Are Investing in AI Life Science Platforms?

Companies are turning to AI life science platforms because they speed up research, improve accuracy, and uncover value hidden in existing data. These tools don’t just save time, they help companies find new opportunities, stay compliant, and work more efficiently with fewer resources. In a competitive industry, that combination is hard to ignore.

1. Faster R&D Cycles

AI platforms are cutting research timelines dramatically by spotting drug targets in days, predicting molecular interactions to reduce lab work by nearly half, and streamlining clinical trial design. One major pharma company even uncovered a new oncology target in just three weeks, a task that used to take well over a year.

2. Higher Research Accuracy

By scanning entire research fields without selection bias, detecting real causal relationships, and constantly validating results against fresh data, AI platforms are helping teams avoid costly errors. One biotech reduced irreproducible results in preclinical studies by more than a third after making the switch.

3. Regulatory Advantage

Compliance-focused AI systems provide fully traceable insights, automatically produce documentation for submissions, and keep detailed version histories. Early adopters have seen FDA submissions move 30% faster thanks to neatly organized, evidence-backed reports.

4. Operational Efficiency

From finishing literature reviews in hours instead of months to prioritizing the most promising experiments and enabling cross-team knowledge sharing, AI tools are boosting productivity across the board. One research institute increased grant-writing efficiency fivefold by automating evidence gathering.

How Does the AI Function in the Causaly Platform?

Causaly’s platform is designed to do one job very well: take the massive, messy world of biomedical literature and turn it into clear, reliable cause-and-effect relationships researchers can actually use. It does this in three main stages: building the knowledge graph, keeping it accurate, and keeping it current.

How Does the AI Function in the Causaly Platform?

1. Building the Causal Knowledge Graph

Collecting the Source Material

To start, Causaly pulls information from the places researchers already trust—peer-reviewed papers in PubMed, early findings on preprint servers like bioRxiv and medRxiv, detailed patent filings, and subscription journals such as Nature, Science, and Elsevier titles—so it’s working with the same sources you’d check yourself, just at a much larger scale.

The system ingests documents in multiple formats:

  • PDFs for published papers and case reports
  • XML from structured scientific datasets
  • Plain text from trial registries and regulatory filings

By accommodating different formats, the platform can work with both modern, structured data and older, scanned or unstructured sources.

Recognizing and Normalizing Entities

Causaly’s NLP is built to spot the important stuff in scientific text, whether it’s a drug like aspirin, a gene like BRCA1, or a disease like Alzheimer’s, and it’s smart enough to know that “TNF-α” and “Tumor Necrosis Factor Alpha” are the same thing, so nothing slips through just because it’s written differently.

Extracting Causal Relationships

Where many tools stop at keyword matching or co-occurrence, Causaly’s models focus on actual causal links, such as:

  • Activation – “Drug A increases Protein B”
  • Inhibition – “Compound X blocks Receptor Y”
  • Associations – “Mutation Z is linked to Disease W”

These models are trained on millions of examples so they can distinguish between a finding that suggests causation and one that simply mentions two items together.

Structuring the Findings

Each verified relationship becomes part of the knowledge graph in a simple but powerful triple format:

Subject → Predicate → Object
(Metforminreduces risk ofcolorectal cancer)

This graph is continuously checked against established biomedical ontologies like MeSH and Gene Ontology to ensure the data is consistent and standardized.


2. Ensuring Accuracy and Reliability

Grounded Answers via RAG

When a user queries the system, the AI uses retrieval-augmented generation, meaning it pulls from the vetted knowledge graph rather than free-text generation from scratch. This keeps answers anchored to actual, verified data.

Automated Fact-Checking

Before adding anything new, Causaly checks it against what’s already in the graph, flags anything that doesn’t line up or lacks solid backing, and gives it a confidence score so you know exactly how strong the evidence is.

Expert Review for High-Stakes Data

For findings that could influence safety, treatment, or regulatory decisions, biomedical experts review the evidence manually before it’s added to the graph.

Transparent Provenance

Each insight comes with its sources, clickable links to the original papers, and the publication date with context, so you can always trace it straight back to where it was first reported.


3. Keeping the Knowledge Graph Up to Date

The platform continuously scans over 5,000 new publications each day across journals, preprints, and clinical updates.

Real-Time Data Pipeline

New research runs through Causaly’s pipeline, first pulled in, then parsed for key entities, analyzed for cause-and-effect, and finally added to the graph—so fresh findings show up almost as soon as they’re published.

Prioritizing Impactful Insights

Not all findings are equal. The system ranks them based on:

  • Citation velocity – how quickly the paper is gaining attention
  • Clinical relevance – potential to influence treatment or research priorities

Versioned Graphs for Historical Context

The graph is stored in versioned snapshots, allowing queries such as:

  • “What was the evidence linking Vitamin D to COVID-19 outcomes in mid-2020?”
  • “How did recommended treatments for breast cancer change between 2015 and 2024?”

Benefits of Building an AI Life Science Platform for a Business

AI life science platforms help businesses speed up research, stay ahead of trends, and ensure transparency. They also boost therapy development, create patent opportunities, and turn data into new revenue streams.

Technical Superiority

1. Unified Biomedical Knowledge Graph

By integrating data from over 30 sources, including clinical trials and patents, AI platforms create a unified, context-rich knowledge graph that reveals causal connections between biological entities. A top pharma company saved 68% of the time needed to identify targets by consolidating previously siloed datasets.

2. Real-Time Research Intelligence

AI-powered systems process thousands of new papers daily, instantly scoring their relevance and updating knowledge graphs within hours. This rapid flow of information helps companies detect emerging trends and disruptive research months ahead of the competition.

3. Transparent, Audit-Ready AI

Every insight generated by AI is fully traceable, with confidence scores and documented evidence trails. The system’s retrieval-augmented approach ensures data integrity, making it both explainable and ready for regulatory audits.


Business Transformation

1. Accelerated Therapy Development

AI platforms speed up drug discovery by optimizing preclinical candidate selection four times faster than traditional methods, cutting patient recruitment time by up to 50%, and improving the likelihood of success in clinical trials. One gene therapy startup reached the IND stage in just 11 months, half the usual time.

2. Market Differentiation

AI enhances intellectual property generation, identifying up to five times more patentable discoveries than manual methods. It also supports precision medicine by enabling biomarker-based strategies and bolstering scientific credibility with AI-curated evidence packages for key opinion leaders.

3. Data Asset Monetization

Life sciences businesses can monetize their research by licensing structured data insights to partners, offering AI-powered analytics tools as a service, and uncovering undervalued therapeutic opportunities, turning raw data into consistent revenue streams.

How to Build an AI Life Science Platform like Causaly?

Building an AI life science platform like Causaly for our clients involves a structured, thoughtful approach that ensures scalability, accuracy, and ease of use. We guide you through every step of the process, from initial strategy to final implementation, making sure your platform is robust, compliant, and truly transformative for your research and operations.

How to Build an AI Life Science Platform like Causaly?

1. Define Your Data Strategy

We begin by identifying the right data sources for your needs—whether it’s literature, clinical trials, patents, or omics data. Ensuring compliance with regulations like HIPAA and GDPR from day one is a priority, so you can rest assured your platform is secure and meets legal standards.


2. Build the Knowledge Core

We create domain-specific ontologies tailored to your research focus, ensuring all your data is organized and standardized. Our team also implements advanced models for entity recognition, relation extraction, and causal inference to map meaningful connections and drive insights.


3. Scalable Cloud & Data Infrastructure

To handle your growing data needs, we build a data lakehouse that supports both structured and unstructured data. Using cloud AI services, we ensure the platform is capable of processing large datasets and computations, providing seamless scalability as your data and processing needs evolve.


4. Generative AI with Scientific Verification

We integrate Retrieval-Augmented Generation pipelines to ensure that all generated insights are directly linked to their source citations, making them traceable and reliable. For critical insights, we incorporate human-in-the-loop review to verify and validate high-stakes findings before they are used.


5. Secure Enterprise Data Integration

We develop APIs that seamlessly integrate your proprietary internal data with public sources, ensuring a smooth flow of information. Security is a priority, so we implement robust access control and encryption to protect sensitive datasets.


6. Develop User Experience 

To make your platform user-friendly, we build natural language search functionalities, allowing researchers to easily query the data. Interactive dashboards are designed to help users explore relationships within the knowledge graph, turning complex data into actionable insights in an intuitive way.

Key Challenges in AI Life Science Platform Development

After working with numerous clients in the life sciences space, we’ve come to understand the common challenges that tend to crop up in AI platform development. Here’s a breakdown of the issues we’ve seen and how we’ve learned to handle them.

1. Ensuring Data Quality & Eliminating Bias

Biomedical data can be a mess, full of contradictions, incomplete studies, and biases from researchers that can mess with AI results.

How We Handle It:

  • Triangulation Approach: We always cross-check data from at least three independent sources before drawing any conclusions. This helps spot inconsistencies and ensures we’re on solid ground.
  • Bias Scoring System: We’ve built algorithms to flag studies that might be problematic, like those with small sample sizes or unclear methods. This way, we can address biases before they affect the AI’s outputs.
  • Expert Review Loops: We keep human experts in the loop, especially for critical decisions like drug safety. That way, we combine the power of AI with the experience of seasoned professionals to catch anything that might slip through the cracks.

2. Scaling for Enterprise Needs

Proof-of-concept systems often crash under the pressure of real-world demands—think thousands of users, millions of documents, and complex queries all happening at once.

How We Handle It:

  • Modular Microservices: Instead of putting everything in one monolithic system, we break it up. Different components like NLP, graph queries, and analytics are independent, so we can scale them separately based on demand.
  • Elastic Cloud Architecture: We use cloud systems that auto-scale during peak periods (like when we’re ingesting large volumes of data) so we never run out of resources when things get busy.
  • Distributed Graph Processing: We split the knowledge graphs into domain-specific parts (for example, oncology or neurology) so queries run faster and more efficiently.

Pro Tip: We recommend starting with containerized services (Docker and Kubernetes) from the get-go. This makes scaling down the road much smoother and more manageable.


3. Meeting Strict Regulatory Requirements

In the life sciences, AI must meet stringent regulatory requirements, including FDA/EMA guidelines, HIPAA, and GxP standards, many of which lack clear guidelines for AI.

How We Handle It:

  • Provenance Tracking: We make sure every AI output has a clear record of where it came from. This way, if anyone needs to trace an output, they can follow the data all the way back to its source.
  • Version Control: We keep an archive of all past versions of the knowledge graph. It’s essential for audits and to ensure that we can always refer back to previous states if needed.
  • Role-Based Access: Sensitive data is locked down. We set up permissions so only the right teams can access high-value IP, ensuring everything stays secure.

Compliance Hack: We’ve had success with AI frameworks designed specifically for regulated environments, like NVIDIA Clara or AWS HealthAI. These systems come pre-configured to meet life sciences requirements, so you don’t have to reinvent the wheel.

Essential Tools for Building an AI Life Science Platform

When building a solid AI-powered platform for life sciences, choosing the right technology stack is critical. Here’s a look at the essential components needed at each stage of development to ensure you create a reliable, scalable, and efficient system:

Essential Tools for Building an AI Life Science Platform

1. Core Infrastructure Components

Cloud Computing Platforms

When it comes to cloud platforms, AWS SageMaker is great for full ML workflows, especially with its HIPAA-compliant options for healthcare data. Google Cloud AI stands out with its pre-trained biomedical NLP models and smooth BigQuery integration for big data analysis. Azure AI is perfect for companies needing hybrid cloud solutions that work seamlessly with on-premise systems.

Pro Tip: Use spot instances for cost-effective model training but reserve dedicated instances for production workloads to ensure stability.

Large-Scale Data Processing

If you’re dealing with massive datasets, Apache Spark is the go-to tool for distributed processing, especially for genomics or literature. Ray Framework shines when you need to parallelize ML tasks across clusters, speeding things up. For a more streamlined approach, Databricks brings everything together, offering both data processing and MLflow for smooth model deployment.


2. AI/ML Development Stack

NLP & Machine Learning Frameworks

TensorFlow and PyTorch are the go-to frameworks for custom deep learning models, offering tons of resources and community support. For biomedical text, Hugging Face Transformers with models like BioBERT and PubMedBERT can save you time and boost NLP performance. 

If you’re diving into large-scale data processing and entity recognition, spaCy is super efficient and well-suited for biomedical tasks.

Critical Add-on: Scispacy: This tool specializes in NLP for scientific and medical texts, enhancing the capabilities of spaCy for life science applications.

Knowledge Graph Technologies

  • Neo4j: A top-tier graph database that uses the Cypher query language, enabling complex relationships and queries within biomedical data.
  • Amazon Neptune: A fully-managed graph database service, ideal for building and querying large-scale knowledge graphs.
  • GraphDB: This semantic graph database supports RDF/OWL standards, making it a solid choice for storing and querying biomedical ontologies.
  • TigerGraph: Designed for ultra-large-scale biomedical knowledge graphs, it’s excellent for high-performance queries across large datasets.

3. Integration & Deployment

API Architectures

REST APIs are perfect for handling basic operations and integrating with external systems. If you’re working with complex, interconnected data, GraphQL makes querying much more efficient, especially for knowledge graphs. For life science-specific data, the BioGraph API is a great choice, as it ensures you’re following the right standards for biological and clinical data.

Specialized Life Science Tools

BioPython is a must-have for anyone working with genomic and molecular data, offering a wide range of bioinformatics tools. RDKit is perfect for cheminformatics, especially in drug discovery and molecular modeling. If you’re diving into drug-target-disease relationships, the OpenTargets API provides curated data to support your research in drug discovery and translational science.


4. Data Management & MLOps

Version Control Systems

DVC (Data Version Control) is essential for tracking your experiments, models, and datasets throughout the entire ML lifecycle. MLflow covers everything from experiment tracking to deployment, making it a comprehensive tool for managing machine learning projects. For large biomedical datasets that go beyond Git’s typical size limits, Git LFS is the way to go for version control.

Monitoring & Validation

  • Weights & Biases: A powerful tool for tracking experiments, managing model performance, and ensuring governance throughout the ML pipeline.
  • Great Expectations: An open-source framework that helps validate data quality and catch errors early in the data pipeline.
  • Evidently AI: Focuses on monitoring production model performance, ensuring that your AI models remain accurate and reliable over time.

Use Case: AI-Powered Drug Repurposing Platform

One of our clients, a mid-sized pharmaceutical company, came to us with a challenge that was putting their bottom line at risk. Their flagship products were hitting patent cliffs, and R&D costs for new drugs were skyrocketing. 

With increasing pressure to reduce time-to-market, they needed a faster, more cost-effective solution, something that could unlock new therapeutic uses for their existing drug portfolio within a year.

The Solution: Building a Smart Repurposing Engine

We developed a custom AI platform that completely redefined their research strategy:

AI-Powered Drug Repurposing Platform

Comprehensive Knowledge Aggregation

We ingested over 4.2 million research papers from PubMed, clinicaltrials.gov, and proprietary datasets. The system also processed 15,000+ drug labels and 230,000 patent documents, and integrated de-identified real-world evidence from electronic health records.

Intelligent Relationship Mapping

The platform built a powerful drug-disease knowledge graph that included 1.7 million established drug-indication relationships and 380,000 novel predicted connections, each scored for confidence to ensure accuracy.

AI-Driven Discovery Workflow

Our AI system found promising repurposing candidates by linking a drug’s mechanisms of action to disease pathways through Mechanistic Matching. We also explored the therapeutic potential of drug side effects using Adverse Effect Reversal and aligned drug effects with specific disease biomarkers in a process we call Biomarker Alignmen.


The Breakthrough Results

Within 8 months, the platform delivered remarkable results:

  • 12 high-probability repurposing candidates (compared to just 2-3 from traditional methods)
  • 3 prioritized leads moved to preclinical validation
  • 1 oncology drug accelerated to a Phase II trial for use in autoimmune disease

Key Outcomes:

  • $42M potential savings compared to developing a new drug
  • 24-month acceleration in pipeline development
  • Created new patent opportunities by leveraging existing intellectual property.

Conclusion

Building an AI life science platform like Causaly is a significant, multi-phase investment that can transform an enterprise’s research capabilities. The key differentiators, causal AI, transparent generative models, and integrated knowledge graphs, are reshaping how life sciences research is done. With the right strategy and execution partner, companies can accelerate innovation and achieve better R&D outcomes.

Looking to Develop an AI Life Science Platform like Causaly?

At IdeaUsher, we specialize in building advanced solutions like Causaly, turning unstructured data into actionable, causal insights. Our AI-powered Life Science platforms streamline complex research, enabling faster discoveries and smarter decision-making. By integrating cutting-edge AI tools, we help you unlock valuable insights, accelerating drug development and clinical trials.

With over 500,000 hours of coding experience and a team of ex-MAANG/FAANG engineers, we deliver:

  • Custom knowledge graphs for drug discovery and research
  • AI-driven literature mining with causal relationship extraction
  • Scalable, compliance-ready platforms for enterprises

Explore our latest projects and let’s create yours, together, we can shape the future of AI-powered life sciences. 

Work with Ex-MAANG developers to build next-gen apps schedule your consultation now

FAQs

Q1. How long does it take to develop an AI life science platform?

A1: Developing a platform like this generally takes between 8 and 18 months. The timeline varies depending on the complexity of the project, the scope of features, and the readiness of the required data. A well-defined plan and available resources can accelerate the process, while unforeseen challenges in data integration or technology can extend the timeline.

Q2. Can a life science platform be upgraded to include causal AI?

A2: Yes, it is possible to upgrade an existing life science platform to incorporate causal AI. This involves modularly adding new capabilities such as natural language processing (NLP) pipelines and integrating knowledge graphs. The process can be tailored to meet the specific needs of the platform, ensuring seamless expansion without overhauling the entire system.

Q3. What industries beyond pharma can benefit from such platforms?

A3: In addition to the pharmaceutical industry, platforms with causal AI capabilities can benefit a range of sectors, including biotech, medical devices, academic research, and public health organizations. These industries can leverage the power of causal analysis to improve decision-making, enhance research outcomes, and drive innovation in product development and health interventions.

Q4. How is data security handled?

A4: Data security is taken very seriously in the development of these platforms. Measures such as end-to-end encryption, robust access controls, and adherence to regulatory compliance frameworks ensure that sensitive data remains protected throughout its lifecycle. These security protocols are designed to safeguard information against unauthorized access while ensuring the platform meets industry standards and regulations.

Picture of Debangshu Chanda

Debangshu Chanda

I’m a Technical Content Writer with over five years of experience. I specialize in turning complex technical information into clear and engaging content. My goal is to create content that connects experts with end-users in a simple and easy-to-understand way. I have experience writing on a wide range of topics. This helps me adjust my style to fit different audiences. I take pride in my strong research skills and keen attention to detail.
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